When organizing a holiday gathering, the choice of tableware might not be the very first thing on the list, but it is an significant one. Without reference to the categorical theme, poinsettia plates are a good complement to other holiday decor. For a party or dinner, these are a terrific way to add colour and holiday cheer.
While the exact pattern may vary, the pretty poinsettia is bound to please all. With historically red flowers and green leaves, it is the perfect color scheme for any vacation party.
It is hard to find anyone that does not admire the great thing about this plant and the design that it inspires. It is a pretty symbol of the vacations that puts everyone in the spirit. The class of the poinsettia is an additional advantage to using this decor theme. It is one that is bound to relay class and sophistication and add to the ambiance of your event. While other holiday decorations could be too specific to a religion, culture, or age group, the poinsettia transcends those limits.
Poinsettia plates can be discovered at most party and cut price stores during the vacations and year-round on the Internet or outlet stores. While pricing may alter dependent on the availability of inventory, they're usually fairly priced thru any of these sellers. This makes them a reasonable way to brighten up your table or buffet, particularly when accompanied by coordinating decor and actual poinsettia plants (available in multiple colours and shades to fill the room).?
The pattern of the plates may also be found on matching serviettes, cups, and table and wall decorations. Which will definitely add some much-needed style to the party. Your party theme can be focused on this lovely design or coordinated with it.Either way, poinsettia plates will have you, your home, and your guests feeling festive, chic, and full of holiday cheer.
Searching for the party store for all your party wishes? Well then you need the party source. Need stuff like plastic wine goblets? What about plastic champagne flutes? We have those too.
Our small business marketing consulting services at craymark.com will help you GROW YOUR BUSINESS NOW. The goal of all businesses is to grow, yet we know that not all experience the growth they hope for. To grow every company needs more leads, more prospects, more customers, and more repeat business. We will help you implement the world reknown Duct Tape Marketing system in your business. This is the very same system utilized by thousands of fast growing businesses around the world. Visit our small business marketing consulting website at http or contact Cray Marketing at (732) 951-2299.
This video frame grab provided by WJLA-TV, taken Wednesday, March 21, 2012, shows Batman, aka Lenny B. Robinson outside his Lamborghini after being pulled over by police in Silver Spring, Md. The driver was dressed as the Dark Knight _ cape, mask and all. Police, however, weren?t impressed and wanted to talk to him about his superhero logo license plate, which isn?t an approved plate in the state. (AP Photo/WLJA-TV)
This video frame grab provided by WJLA-TV, taken Wednesday, March 21, 2012, shows Batman, aka Lenny B. Robinson outside his Lamborghini after being pulled over by police in Silver Spring, Md. The driver was dressed as the Dark Knight _ cape, mask and all. Police, however, weren?t impressed and wanted to talk to him about his superhero logo license plate, which isn?t an approved plate in the state. (AP Photo/WLJA-TV)
This video frame grab provided by WJLA-TV, taken Wednesday, March 21, 2012, shows Batman, aka Lenny B. Robinson outside his Lamborghini after being pulled over by police in Silver Spring, Md. The driver was dressed as the Dark Knight _ cape, mask and all. Police, however, weren?t impressed and wanted to talk to him about his superhero logo license plate, which isn?t an approved plate in the state. (AP Photo/WLJA-TV)
ROCKVILLE, Md. (AP) ? Police in Maryland pulled over a motorist dressed as Batman, but the caped crusader escaped without a ticket.
Authorities pulled over the driver of a black Lamborghini with Batman logo tags last week in Silver Spring outside Washington. The driver was dressed as the Dark Knight ? cape, mask and all. Police, however, weren't impressed and wanted to talk to him about his superhero logo license plate, which isn't an approved plate in the state.
The driver, who goes by Lenny B. Robinson when not dressed as a superhero to visit sick children at hospitals, was able to show them a proper license plate for the car. A video of the stop shows police officers shaking his hand and taking pictures of him with his ride.
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Tags: article writing service, buy articles for website, buy articles for your website
Targeted medications effective at clearing skin condition
Web edition : 9:38 am
Two experimental drugs given to patients with psoriasis can clear the skin condition?s characteristic thick, dry, red patches at unprecedented rates. The finding paves the way for the long-term clinical trials required for regulatory approval of the medications.
By toning down a key immune protein, the drugs wipe out many psoriasis plaques while showing few signs of side effects. Studies of the two drugs appear in the March 29 New England Journal of Medicine.
Provided major adverse effects don?t turn up in long-term tests, the two medications have a bright future, says Andrew Blauvelt, an immunologist and dermatologist at the Oregon Medical Research Center in Portland. ?So far, these are looking like great drugs.?
Craig Leonardi, a dermatologist at the Saint Louis University School of Medicine, was part of both teams that tested the drugs, called ixekizumab and brodalumab. He and other researchers scored the severity of the patients? psoriasis based on precise measurements of skin affected by the hallmark red plaques. A successful drug reduces a patient?s severity score by 75 percent.
All volunteers had had moderate to severe psoriasis affecting at least 10 percent of their bodies for six months. In one of the studies, Leonardi and his colleagues randomly assigned 142 patients to receive either ixekizumab or a placebo. In the other, 198 patients got brodalumab or placebo. In both studies, drugs and placebo were delivered as several injections spaced over 12 to 16 weeks, using various doses.
Both drugs reduced the psoriasis severity score by 75 percent in about four-fifths of patients getting a medium to high dose of either drug.
The drugs thwart the immune protein interleukin-17. In most people this protein plays a productive role, fending off bacterial and fungal infections, Blauvelt says. But people with psoriasis overproduce interleukin-17, which induces activation and growth of the outer-layer skin cells that make keratin. Only long-term testing, some of which is already under way, will establish that interleukin-17 activity can be suppressed by these new drugs indefinitely without risk of infection, Blauvelt says.?
Each study was funded by the drug?s manufacturer. Eli Lilly makes ixekizumab, and Amgen makes brodalumab.
Blauvelt says the new results compare favorably with previous early-stage studies of drugs that also target immune system proteins implicated in psoriasis. Some of these drugs have reached pharmacy shelves as etanercept (Enbrel), adalimumab (Humira) and ustekinumab (Stelara).
The last 10 years have seen ?a very profound shift in the approach to treatment of psoriasis,? says dermatologist Kim Papp of Probity Medical Research, in Waterloo, Ontario, Canada, and coauthor of the brodalumab study.
And the targeted approach has vastly improved options for patients, Leonardi adds. ?Fifteen to 20 years ago was still the therapeutic Stone Age [for psoriasis treatment] with the use of coal tar and ultraviolet light,? says Leonardi, who reports consulting for Amgen, Eli Lilly and other companies. He envisions that the two new drugs, if approved, will be lifelong injectable medications ? just as insulin is for diabetes. ?Chronic diseases require chronic therapies,? he says.
Yesterday, I wrote a post about the 4 types of keywords for your video marketing success where I gave you a list of 4 different types of keywords you can use to really boost your video marketing efforts.? In that post I promised you I would give you some video marketing keyword research tips to help you find those ideal keywords to use as topics of your videos.? Keywords for video marketing are much different than keywords you would use to drive traffic to your website.? I never like to disappoint, so here are your video marketing keyword research tips:
1.???? Use Google Keyword Tool to see what keywords people are searching for that are related to real estate.? Look for keywords with 3,000 + local monthly searches.? Write those down and actually search those keywords for videos.
2.???? Reverse engineering your competitors? videos is a great way to do some reconnaisance work.? This is done by clicking on the graph button underneath the video player to the right of the display of the number of video views.? You can see lots of interesting demographics and stats as to who is watching your competitions? videos, why the video gets the views, and where the views are coming from (which keywords are being used to find the videos).
3.???? Look for keywords with upward trends using Google Insights.? You are looking for keywords that have an upward trend rather than downward (or flat).? Keywords trending up are being searched more frequently than downward trending videos. ?However, as you can see by the chart below, our industry is trending downward.? So, think about what your family, friends, and clients are asking you about that is real estate related and search those trends, ie foreclosures, short sales, etc.
4.???? Follow http://www.twitter.com/#!/YouTubeTrends? to see what is trending on YouTube.? This is a great way to get current event keywords that we discussed in yesterday?s post.
5.???? If you are not on Twitter, then go to http://youtube-trends.blogspot.com/ to see what is hot on YouTube right now.
5.5This really doesn?t have to do with your keyword research, but it is not a bad idea to watch your competition closely.? Do this by going to Google Alerts and setting up video alerts for your keywords to see who is posting videos related to your subject.
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Try these 5.5 tips when you are researching keywords for your video topics, and you will be far ahead of your competition.? Following this system will lead to more views for your videos and more business due to more exposure from those views.? If you have another great strategy for researching keywords for real estate video marketing, then please leave that below in the comments section.
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Tags: video marketing for real estate, video marketing for real estate agents, YouTube for Real Estate
Annual cost of autism has more than tripled - $126 billion US and 34 billion in the UK Public release date: 28-Mar-2012 [ | E-mail | Share ]
Contact: Jane E. Rubinstein jrubinstein@rubenstein.com 212-843-8287 Autism Speaks
Lifetime care of individuals with autism highest for those with intellectual disability $2.3 million US and 1.5 million UK
New York, N.Y. Autism Speaks, the world's leading autism science and advocacy organization, today announced preliminary results of new research that estimates autism costs society a staggering $126 billion per year (U.S.) a number that has more than tripled since 2006, and annually in the U.K. has reached more than 34 billion (equivalent to $54 billion U.S.). The costs of providing care for each person with autism affected by intellectual disability through his or her lifespan are $2.3 million in the U.S. and 1.5 million ($2.4 million) in the U.K. The lifetime costs of caring for individuals who are not impacted by intellectual disability are $1.4 million in the U.S. and 917,000 in the U.K. (equivalent to $1.46 million). The Autism Speaks-funded research, conducted by researchers Martin Knapp, Ph.D., of the London School of Economics, and David Mandell, Sc.D., of the University of Pennsylvania, will be presented at the international conference "Investing in our Future: The Economic Costs of Autism," hosted by Goldman Sachs in collaboration with the Child Development Centre and Autism Speaks, on March 31 in Hong Kong.
Drs. Knapp and Mandell compiled information from recent studies of autism costs from multiple sources to calculate the current cost of autism associated with the current CDC-reported prevalence that 1:110 children are diagnosed with an autism spectrum disorder (ASD). The cost of autism continues to grow with the rise in prevalence. While the latest prevalence estimates in the U.S. and U.K. are comparable, the primary difference in total costs of autism in the U.S. and U.K. are due to differences in total country population (five times larger in the U.S. than the U.K.). The research team found that the cost of autism in the U.S. alone is greater than the entire Gross Domestic Product (GDP) of 139 countries around the world.
Bob Wright, co-founder of Autism Speaks, said, "Autism is a global public health crisis. The costs are staggering and will continue to rise as prevalence continues to increase. We know that early diagnosis and treatment are critical, so it is imperative that the U.S. and governments around the world step up their commitment to helping people living with autism today. The investment we make now is essential to reducing the long-term costs of autism."
This research found that intellectual disability plays a major role in the cost of autism to individuals, families, and society as a whole. The costs of autism per year are nearly twice as high on average for children and adults with intellectual disability than for children and adults without intellectual disability, $2.3 million in the U.S. and 1.5 million in the U.K. ($2.4 million) for those individuals who are impacted by intellectual disability compared with more than $1.4 million in the U.S. and 917,000 ($1.46 million) in the U.K. for those who do not have intellectual disability.
A number of factors were considered by the researchers that contributed to the cost differential between U.S. and U.K. lifetime and total costs. The education and healthcare systems in the two countries offer different responses to the needs of people with autism and their families. Access to empirical data regarding healthcare and education costs differed between the two countries. It is also currently estimated that 45 percent of individuals with ASD in the U.S. and 55 percent of individuals with ASD in the U.K. have intellectual disabilities, defined as an IQ of 70 or less. Experts consistently point to early interventions as key to increasing language and IQ scores, and reducing life span costs.
Total costs to the U.S. were also based on adult prevalence of one-half of one percent, lower than currently estimated 1:110 prevalence of autism in children, derived from past CDC studies. The researchers point to adult prevalence as an area for additional study in the U.S.
The research also found that non-medical costs account for the greatest proportion of expenses. While direct medical costs, such as outpatient care, home care, and pharmacy, contribute significantly to overall expenses, non-medical costs, including intervention services and special education, child daycare, and especially residential placements and care for adults who age out of school and can no longer live at home with parents account for the largest proportion of autism costs.
"The burden on families affected by autism is enormous," continued Autism Speaks President Mark Roithmayr. "The extraordinary cost further exacerbates that burden. The time and effort involved in coordinating the care and treatment plan across a large number of providers has reduced the ability of many families to earn a living. Too many families are still denied insurance coverage for essential treatments and services, and the economics add to overall emotional burden on families."
Building on this preliminary research, Autism Speaks recently provided additional funding to Drs. Knapp and Mandell to support an additional year of study to examine how autism therapies reduce lifetime costs associated with autism. Their investigation will focus on both intensive preschool behavioral interventions and vocational interventions that support an individual's independence during the transition to adulthood. Calculations will take into account costs related to healthcare, education, caregiving, housing, and employment.
As confirmed by this study, the majority of costs related to autism are incurred during adulthood, principally due to the cost of residential care as well as loss of productivity, underemployment and unemployment among adults with autism. Services for adults are both lacking and expensive.
In 2007, Michael L. Ganz, Ph.D. of the Harvard School of Public Health published research in the journal Archives of Pediatric and Adolescent Medicine which estimated that autism cost the United States more than $35 billion per year, and that the incremental cost of caring for an individual with autism over his or her lifetime due to their special needs was more than $3 million. Despite growing prevalence, autism currently receives less than five percent of the research funding of many less prevalent childhood diseases and disorders.
Dr. Mandell added, "We are paying for the costs of inaction and the costs of 'inappropriate action.' Social exclusion of individuals with autism and intellectual disability, and exclusion of higher-functioning individuals from employment opportunities are increasing the burden not only on these individuals and their families, but on society as a whole."
Dr. Mandell and his colleagues recently published findings in Pediatrics that mothers of children with ASD are less likely to work, work fewer hours per week and earn substantially less. Typically the primary caregiver, mothers are called upon to serve as their child's case manager and advocate, and on average, earn 56 percent less than mothers of children with no health limitations. They earn 35 percent less than mothers of children with another health limitation. They are 6 percent less likely to be employed, and they work an average of seven hours less per week.
Dr. Knapp, Professor of Social Policy at the London School of Economics and Political Science and a preeminent expert on health economics explained that the economic burden of autism varies widely across different parts of society from the individuals with ASD, their families, the communities they live in, businesses in those communities, to the government agencies which provide healthcare, education, welfare benefits, social care, and housing. "There is an immediate need for better coordination across public agencies and levels of government from local to national in the way that society structures its service delivery system; too often responses to the needs of individuals and families are piecemeal and less helpful than they could be," he concluded.
###
This research was wholly funded by Autism Speaks. The World Health Organization (WHO), through its partnership with Autism Speaks, is serving in an advisory capacity and providing technical support for the cost of autism analysis.
About Autism
Autism is a general term used to describe a group of complex developmental brain disorders autism spectrum disorders caused by a combination of genes and environmental influences. These disorders are characterized, in varying degrees, by social and behavioral challenges, as well as repetitive behaviors. An estimated 1 in 110 children in the U.S. is on the autism spectrum a 600 percent increase in the past two decades that is only partly explained by improved diagnosis.
About Autism Speaks
Autism Speaks is the world's leading autism science and advocacy organization. It is dedicated to funding research into the causes, prevention, treatments and a cure for autism; increasing awareness of autism spectrum disorders; and advocating for the needs of individuals with autism and their families. Autism Speaks was founded in February 2005 by Suzanne and Bob Wright, the grandparents of a child with autism. Mr. Wright is the former vice chairman of General Electric and chief executive officer of NBC and NBC Universal. Since its inception, Autism Speaks has committed over $173 million to research and developing innovative resources for families. Each year Walk Now for Autism Speaks events are held in more than 95 cities across North America. To learn more about Autism Speaks, please visit www.autismspeaks.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Annual cost of autism has more than tripled - $126 billion US and 34 billion in the UK Public release date: 28-Mar-2012 [ | E-mail | Share ]
Contact: Jane E. Rubinstein jrubinstein@rubenstein.com 212-843-8287 Autism Speaks
Lifetime care of individuals with autism highest for those with intellectual disability $2.3 million US and 1.5 million UK
New York, N.Y. Autism Speaks, the world's leading autism science and advocacy organization, today announced preliminary results of new research that estimates autism costs society a staggering $126 billion per year (U.S.) a number that has more than tripled since 2006, and annually in the U.K. has reached more than 34 billion (equivalent to $54 billion U.S.). The costs of providing care for each person with autism affected by intellectual disability through his or her lifespan are $2.3 million in the U.S. and 1.5 million ($2.4 million) in the U.K. The lifetime costs of caring for individuals who are not impacted by intellectual disability are $1.4 million in the U.S. and 917,000 in the U.K. (equivalent to $1.46 million). The Autism Speaks-funded research, conducted by researchers Martin Knapp, Ph.D., of the London School of Economics, and David Mandell, Sc.D., of the University of Pennsylvania, will be presented at the international conference "Investing in our Future: The Economic Costs of Autism," hosted by Goldman Sachs in collaboration with the Child Development Centre and Autism Speaks, on March 31 in Hong Kong.
Drs. Knapp and Mandell compiled information from recent studies of autism costs from multiple sources to calculate the current cost of autism associated with the current CDC-reported prevalence that 1:110 children are diagnosed with an autism spectrum disorder (ASD). The cost of autism continues to grow with the rise in prevalence. While the latest prevalence estimates in the U.S. and U.K. are comparable, the primary difference in total costs of autism in the U.S. and U.K. are due to differences in total country population (five times larger in the U.S. than the U.K.). The research team found that the cost of autism in the U.S. alone is greater than the entire Gross Domestic Product (GDP) of 139 countries around the world.
Bob Wright, co-founder of Autism Speaks, said, "Autism is a global public health crisis. The costs are staggering and will continue to rise as prevalence continues to increase. We know that early diagnosis and treatment are critical, so it is imperative that the U.S. and governments around the world step up their commitment to helping people living with autism today. The investment we make now is essential to reducing the long-term costs of autism."
This research found that intellectual disability plays a major role in the cost of autism to individuals, families, and society as a whole. The costs of autism per year are nearly twice as high on average for children and adults with intellectual disability than for children and adults without intellectual disability, $2.3 million in the U.S. and 1.5 million in the U.K. ($2.4 million) for those individuals who are impacted by intellectual disability compared with more than $1.4 million in the U.S. and 917,000 ($1.46 million) in the U.K. for those who do not have intellectual disability.
A number of factors were considered by the researchers that contributed to the cost differential between U.S. and U.K. lifetime and total costs. The education and healthcare systems in the two countries offer different responses to the needs of people with autism and their families. Access to empirical data regarding healthcare and education costs differed between the two countries. It is also currently estimated that 45 percent of individuals with ASD in the U.S. and 55 percent of individuals with ASD in the U.K. have intellectual disabilities, defined as an IQ of 70 or less. Experts consistently point to early interventions as key to increasing language and IQ scores, and reducing life span costs.
Total costs to the U.S. were also based on adult prevalence of one-half of one percent, lower than currently estimated 1:110 prevalence of autism in children, derived from past CDC studies. The researchers point to adult prevalence as an area for additional study in the U.S.
The research also found that non-medical costs account for the greatest proportion of expenses. While direct medical costs, such as outpatient care, home care, and pharmacy, contribute significantly to overall expenses, non-medical costs, including intervention services and special education, child daycare, and especially residential placements and care for adults who age out of school and can no longer live at home with parents account for the largest proportion of autism costs.
"The burden on families affected by autism is enormous," continued Autism Speaks President Mark Roithmayr. "The extraordinary cost further exacerbates that burden. The time and effort involved in coordinating the care and treatment plan across a large number of providers has reduced the ability of many families to earn a living. Too many families are still denied insurance coverage for essential treatments and services, and the economics add to overall emotional burden on families."
Building on this preliminary research, Autism Speaks recently provided additional funding to Drs. Knapp and Mandell to support an additional year of study to examine how autism therapies reduce lifetime costs associated with autism. Their investigation will focus on both intensive preschool behavioral interventions and vocational interventions that support an individual's independence during the transition to adulthood. Calculations will take into account costs related to healthcare, education, caregiving, housing, and employment.
As confirmed by this study, the majority of costs related to autism are incurred during adulthood, principally due to the cost of residential care as well as loss of productivity, underemployment and unemployment among adults with autism. Services for adults are both lacking and expensive.
In 2007, Michael L. Ganz, Ph.D. of the Harvard School of Public Health published research in the journal Archives of Pediatric and Adolescent Medicine which estimated that autism cost the United States more than $35 billion per year, and that the incremental cost of caring for an individual with autism over his or her lifetime due to their special needs was more than $3 million. Despite growing prevalence, autism currently receives less than five percent of the research funding of many less prevalent childhood diseases and disorders.
Dr. Mandell added, "We are paying for the costs of inaction and the costs of 'inappropriate action.' Social exclusion of individuals with autism and intellectual disability, and exclusion of higher-functioning individuals from employment opportunities are increasing the burden not only on these individuals and their families, but on society as a whole."
Dr. Mandell and his colleagues recently published findings in Pediatrics that mothers of children with ASD are less likely to work, work fewer hours per week and earn substantially less. Typically the primary caregiver, mothers are called upon to serve as their child's case manager and advocate, and on average, earn 56 percent less than mothers of children with no health limitations. They earn 35 percent less than mothers of children with another health limitation. They are 6 percent less likely to be employed, and they work an average of seven hours less per week.
Dr. Knapp, Professor of Social Policy at the London School of Economics and Political Science and a preeminent expert on health economics explained that the economic burden of autism varies widely across different parts of society from the individuals with ASD, their families, the communities they live in, businesses in those communities, to the government agencies which provide healthcare, education, welfare benefits, social care, and housing. "There is an immediate need for better coordination across public agencies and levels of government from local to national in the way that society structures its service delivery system; too often responses to the needs of individuals and families are piecemeal and less helpful than they could be," he concluded.
###
This research was wholly funded by Autism Speaks. The World Health Organization (WHO), through its partnership with Autism Speaks, is serving in an advisory capacity and providing technical support for the cost of autism analysis.
About Autism
Autism is a general term used to describe a group of complex developmental brain disorders autism spectrum disorders caused by a combination of genes and environmental influences. These disorders are characterized, in varying degrees, by social and behavioral challenges, as well as repetitive behaviors. An estimated 1 in 110 children in the U.S. is on the autism spectrum a 600 percent increase in the past two decades that is only partly explained by improved diagnosis.
About Autism Speaks
Autism Speaks is the world's leading autism science and advocacy organization. It is dedicated to funding research into the causes, prevention, treatments and a cure for autism; increasing awareness of autism spectrum disorders; and advocating for the needs of individuals with autism and their families. Autism Speaks was founded in February 2005 by Suzanne and Bob Wright, the grandparents of a child with autism. Mr. Wright is the former vice chairman of General Electric and chief executive officer of NBC and NBC Universal. Since its inception, Autism Speaks has committed over $173 million to research and developing innovative resources for families. Each year Walk Now for Autism Speaks events are held in more than 95 cities across North America. To learn more about Autism Speaks, please visit www.autismspeaks.org.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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LED Kitchen Lighting An Excellent Strategy To Make Kitchen Area Desirable And Amazing
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Kentucky head coach John Calipari, left, speaks during a news conference, Saturday, March 24, 2012, in Atlanta. Kentucky is scheduled to play Baylor in the NCAA college basketball tournament South Regional finals on Sunday, March 25. (AP Photo/David J. Phillip)
Kentucky head coach John Calipari, left, speaks during a news conference, Saturday, March 24, 2012, in Atlanta. Kentucky is scheduled to play Baylor in the NCAA college basketball tournament South Regional finals on Sunday, March 25. (AP Photo/David J. Phillip)
Kentucky head coach John Calipari speaks during a news conference, Saturday, March 24, 2012, in Atlanta. Kentucky is scheduled to play Baylor in the NCAA college basketball tournament South Regional finals on Sunday. (AP Photo/David J. Phillip)
Baylor head coach Scott Drew speaks during a news conference Saturday, March 24, 2012, in Atlanta. Baylor plays Kentucky in an NCAA tournament South Regional final college basketball game on Sunday. (AP Photo/David J. Phillip)
Kentucky's Anthony Davis makes his way to a news conference, Saturday, March 24, 2012, in Atlanta. Kentucky is scheduled to play Baylor in the NCAA college basketball tournament South Regional finals on Sunday. (AP Photo/David J. Phillip)
Kentucky's Darius Miller listens to a question during a news conference, Saturday, March 24, 2012, in Atlanta. Kentucky is scheduled to play Baylor in the NCAA college basketball tournament South Regional finals on Sunday. (AP Photo/David J. Phillip)
ATLANTA (AP) ? John Calipari is having a ball. Well, except for movie night.
The coach of top-seeded Kentucky has avoided watching other games during the NCAA tournament, and he wants his players to do the same. His message: Focus on us and don't worry about other teams.
So far, it's working just fine. The Wildcats (35-2) are one win away from a return trip to the Final Four. They'll face Baylor (30-7) in the South Regional final Sunday.
Calipari knows he's got an extremely talented group, and he's having a great time coaching them. When on the road, the Wildcats usually head to the movies, so they're not stuck in the hotel room watching other games.
After arriving in Atlanta, they went to see "21 Jump Street." Calipari's assessment: "Awful."
ScienceDaily (Mar. 23, 2012) ? An international team of scientists, including some from Majorca and the Canary Islands, have described a new type of fossil scops owl, the first extinct bird on the archipelago of Madeira (Portugal). Otus mauli, which was also the first nocturnal bird of prey described in the area, lived on land and became extinct as a result of humans arriving on the island.
Twenty years ago, the German researcher Harald Pieper discovered fossil remains of a small nocturnal bird of prey in Madeira, which, until now, had not been studied in depth. The international team of palaeontologists has shown that the remains belong to a previously unknown extinct species of scops owl, which they have called Otus mauli.
"It has long legs and wings slightly shorter than the continental European scops owl from which it derives" Josep Antoni Alcover, one of the authors of the study and researcher at the Mediterranean Institute for Advanced Studies (IMEDEA), a mixed centre of the university of the Balearic Islands and the Spanish National Research Council (CSIC), said.
The result of the analysis of the proportions of the remains found, which has been published in the journal Zootaxa, reveals that Otus mauli could be a land inhabiting species that ate invertebrates and "occasionally lizards or birds."
"It is likely that their extinction is linked to the arrival of humans and the fauna they brought with them," Alcover explains. He also points out that their disappearance formed part of a pattern of extinction of the island's species, which occurred in virtually all the islands of the world.
According to researchers, amongst the causes of extinction of this scops owl, the destruction of its habitat is highlighted, as Madeira had a lot of serious fires during the seven years that followed the Portuguese arrival. Furthermore, humans brought new birds with diseases that were unfamiliar to the native species, as well as rats and mice that could prey on eggs of animals that had nests close to the ground.
Exclusive to Madeira?
The same or a similar species has been investigated in Porto Santo, another island of the archipelago of Madeira. "This is extremely interesting" the researcher says, "but difficult to assess because the materials found are limited and fragmented."
"If the scops owls of Madeira and Porto Santo were different species, it would mean that the Otus' flying ability is much more limited than continental scops owls. The distance between the two islands would be enough to isolate them" Alcover points out.
The homogeneity of the scops owls' measurements on the two islands, as well as the differences compared to European scops owls suggests that they were genetically isolated from the European populations. The distance between the continent and the island was enough to explain the difference in the species.
On this island they expect to discover new species of birds in the near future "which will report a world that disappeared just a few hundred years ago." "The same thing will happen in the Azores islands where there is already evidence that a scops owl different to the ones in Madeira and Europe that is also extinct" the scientist says.
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The above story is reprinted from materials provided by Plataforma SINC, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
Rando J.C.; Pieper H.; Alcover J.A.; Olson S.L. A new species of extinct fossil Scops owl (Aves: Strigiformes: Strigidae: Otus) from the Archipelago of Madeira (North Atlantic Ocean). Zootaxa, 2012
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Quit smoking is the toughest task of all time. Every time people try to quit smoking they fail to do so. Electric cigarettes are the device of digital world. One can experience lot more with electric cigarette.
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Lots of of us wanting to consider our workout routines to the next degree have explored the concept of employing a personal trainer at some point. For some, the attractiveness is the complete knowledge base of the skilled qualified, for others its the increased accountability of holding an appointment, and nonetheless other individuals want the one-on-one interaction and custom-made exercises to meet their own individual goals. Regardless of the cause, on the other hand, there are two primary factors that preserve several of us from selecting ? time and dollars. We require a resolution that may cater to our budgets and daily schedules.
A new net trend is performing just that. The ?online personal trainer? is coming towards the rescue of an escalating variety of budget-conscious, over-scheduled People in america, presenting the newest remedy to assist us learn our fitness objectives. Though some may possibly argue the on-line plans can never ever specifically duplicate the encounter of getting a trainer at your facet in the course of your exercise, the designers of those applications have gone to wonderful lengths to match and, in some instances, strengthen the overall benefits that you simply obtain.
As youd when employing a private trainer face-to-face, you need to question concerns and study the many programs and providers to locate the system that functions finest for you.
Meeting Your Personal Demands
As our personalities vary so do our personal coaching desires.
You can find a variety of solutions at the moment becoming provided on the internet from auto-generated weekly workout routines to customized workout routines designed by trainers who interact with their clientele frequently by way of email or live immediate messaging.
If it is actually just the fundamental information that you simply want, subscribing to a service that just supplies you with a weekly workout may be the best match for you personally. The majority of the company providers have some implies of evaluation to provide you having a beginning work out according to your health degree, so it is actually critical to answer these questions actually so that you can get the work out that the majority intently fits your demands. That you are sent physical exercise programs frequently and expected to adhere to them on your personal. These programs are developed to satisfy the demands of people persons that are determined to operate out and basically require a program to keep them heading in the right direction from week to week.
For those who genuinely desire to preserve the ?personal? in personal trainer, some support companies supply the additional choice of getting direct interaction having a coach through email or immediate messaging. Just how much interaction you get often is dependent upon the degree of company plan that you just decide on, having said that, just about all deliver a less costly choice for the standard approach to personal instruction.
Much more Bang for your Buck
If you?ve ever before asked a personal trainer for their rates and gone into instant sticker shock, you?re not on your own. The current, typical price for any licensed private coach is $60-$90 for every hour. Multiply that by two to three hours per week you?re easily taking a look at hundreds of dollars monthly. In short, that type of cost just isn?t an alternative for quite a few of us.
On the net personal coaching providers, like quite a few world-wide-web company offerings, are discounted since firms are able to support a considerably bigger consumer base with less overhead. The automated programs are clearly the cheapest option simply because they require no real human interaction.
If youd like the customization and one-on-one advice of a personal trainer so that you might have an individual in your aspect as you work towards your goals, numerous web sites have an prolonged service that gives you access into a live individual. Once again, services amounts and costs vary depending around the provider. For instance, some websites permit you to e-mail your private trainer, delivering an implies for inquiring queries. A new web site, LiveLeanToday, is getting the interaction one stage farther to supply its personal training clientele with day-to-day access to their coach by way of Instant Messaging. Clientele may have the capacity to open up a chat window with their coach through which they can carry on an actual time discussion.
?Our mission would be to offer our customers using the assistance they must come to be fit for life,? claims Chuck Carter, president of LiveLeanToday. ?In effect, we?re supplying them with a lot more access than theyd have whenever they employed an individual coach at a gym to get a smaller fraction in the price tag. Theyve daily access to their trainers for inquiring concerns, finding just a little added assistance within the poor times or encouragement within the superior ones.?
Creating Health Match Your Day
Because the American lifestyle carries on to obtain more hectic, on the net trainers are assisting people fit fitness into their lives. Customarily, choosing a coach has meant coordinating your routine with theirs. The issue is that far more generally than not, the hours that you simply are readily available ? commonly just before perform or immediately after ? are precisely the same hrs as those of every other consumer a coach has.
The on line private coach solves this concern by making your instruction plans obtainable for download anytime. Since your exercise will not be dependent on an individual else?s schedule, that you are absolutely free to match your work out in every time you may have some time. Furthermore, considering the fact that contact with your trainer requires spot electronically, the trainers can operate with a number of clients at the similar time creating them more available as opposed to in-gym trainers that only work through appointment.
Surrounded by Assistance
For those of us who have made use of a private coach before, we realize that there are many additional hours inside the week compared to two or three that were basically in a position to devote with our trainers. Its simple to remain motivated in the existence of our trainers, but what happens when we go away the gym and attempt to fit our goals into our day-to-day lives This really is one area where one on the net instruction internet site in distinct actually excels.
A newcomer for the on-line community, LiveLeanToday, presents regions that allow you to talk to other men and women who are working in the direction of physical fitness targets equivalent to yours. The message boards give a discussion board for sharing recommendations and encouragement when you progress. It?s an excellent medium for swapping recipes and attaining somewhat extra determination on people times which you just don?t feel like working out, and its the perfect location to share your successes with people today progressing toward the exact same targets as you happen to be.
According to Bryan Ashbaugh, CEO of LiveLeanToday, the community aspect is just as critical for the general good results of many clients as a superb eating plan and working out.
?In my 8 many years of helping individuals reach their conditioning objectives, I?ve identified the plan is usually only as great as that person?s system of support, that is truly outside of the attain of a private trainer,? claims Ashbaugh.
?At Reside, we desired to supply a forum for our customers exactly where there could be absolutely nothing but positive encouragement from peers experiencing exactly the same difficulties and working toward related objectives.By delivering our clients with a support system, which they may possibly not usually have, as component of our program, they?ll generally have a source of encouragement to help them remain on course.?
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Kerry Packer James Packer Crown Casino Crown Limited Art Television Publicity Media Man
Media Man revisits one of their most popular news stories from 2010...
G'day punters, casino and gambling millionaires and billionaires, media magnates, journalists, historians and art lovers. Art lovers?! Yes, today we bring you a special Kerry Packer special. The legend lives on, not only here, but now at an Australian artists exhibition, and of course 'Our James' (James Packer) continues to fly the flag and do the family legacy proud with his Crown Limited empire. Not only that, we also cover the pending return of KP to Australian television in an ABC mini series tipped to hit the jackpot, and Network Nine is bringing back 'Underbelly', complete with gambling themes. Media Man and Gambling911 present The Kerry Packer Special...
Kerry Packer & Friends...
Kerry Packer & Friends - NG Art Gallery - 7th Dec - 24th Dec 2010
3 Little Queen Street
Chippendale, NSW Sydney AUSTRALIA
Tuesday - Saturday 11.00am - 5.30pm
Ok punters, here's the rundown. The artist - storyteller is Gina Sinozich. She's an 80 year old, Croat, Sydney based artist who paints in order to help recycle memory. Sinozich's latest exhibition, Kerry Packer and Friends, is her first solo commercial effort in Sydney and is tells the story of the legendary Kerry Packer. She covers the unique personality and complexities of a legend who was known for his astronomical wealth, super whale gambling exploits, running his business with an iron fist, and colourful run ins with the Australian government, amongst other things.
Sinozich migrated down under to Australia is 1956 and began to paint at the age of 75, now having work in Australian and New Zealand corporate and public collections. Her show showcases Packer as 'one of us' rather than the untouchable media tycoon. Sinozich was inspired to tell the story on the premise that we often hear bad before good. This tribute to KP is generous and reveals alot of the most powerful men in the world, who in 2004, was estimated to have a net worth of AUD 6.5 billion. The work of Sinozich will be showcased at NG Art Gallery from the 7th-24th of December and is certain to excite audiences, punters, art lovers or both. A fews Aussie commentator think this blows away much of the art that American gambling tycoon Steve Wynn shows off. Maybe Wynn might like to make a purchase of some classic Packer creations.
Sinozich says Packer gave back to society in a meaningful way and the series was intended to stand as a testament for this man's intrinsic goodwill after his death in December 2005. She recites a story that fuelled her initial interest in Packer, "...one lady said that she was on George Street with two little kids behind her and she was running...running to go on the train, and he (Packer) stopped her and said, 'don't you have a car?' and he wrote a cheque for her and said here, 'buy yourself a car'." Sinozich also fondly recalls, "...when he was playing in casino in Perth he won so much money and the girl who was serving wine...he asked her, 'do you have a mortgage on the house?' she said 'yes', then he wrote a cheque for AUD 600,000."
The talented, even cunning, artist worked like a Trojan horse for a fortnight and managed to produce 26 paintings that deeply explore her subject's nature, removing much of the mystic of Packer as an uncompromising media mogul. All the characters in Sinozich's work have a yarn to tell, and most aspects of his life are covered... birth, death, and much of the in between. Make no mistake, the works are smart, and unique, and are tipped to become collectors items.
The work is relatively simple, but full of life, and has been described as "traditional representational painting", which one may argue is a dying art. We think KP would have liked the tribute, and we await word to see what living members of the Packer clan think of the works.
Kerry Packer Legend To Return To Australian TV In Cleo Mini Series...
Packer is to return to life on Aussie TV via new ABC drama Paper Giants: The Birth Of Cleo (not to be confused with the Cleopatra slot game).
Australian readers may recall the public backlash to the introduction of the super sexy womens? title in 1972. There were Cleo lovers and haters, but we're still talking about it today, so it made an impact, which is better than many of today's rags.
Rob Carlton will play a young Packer opposite Asher Keddie as publishing pioneer, the sexy and smart Ita Buttrose.
Rumours of a sexual relationship between Packer and Ita around the time of Cleo magazine's start off, but this won't be a focus on the mini-series, due to air next year.
Buttrose, who first made her mark as the magazine's editor, was a consultant on the production.
"If there was a supposed affair it didn't happen in this timeframe. I have no idea if there was, we didn't raise it with her," Edwards said.
There ABC publicity brief has whet our appetite for lots of Packer classic stuff and enough scandal to keep us coming back for more.
"It's 1972. Skirts are up, pants are down. Girls can have anything: Fabulous careers, fashionable clothes and oral sex," spruiks the promo.
The drama cleverly follows the death of Sir Frank Packer and the rise of his second son, who defies even family expectation to succeed, in a way no one could have expected.
"It was a real turning point in Kerry's career. It was a period when he made his first big move and it was an astonishing success and one against the odds in some respects," Edwards said.
Cleo magazine itself was a fine, yet controversial work, and introduced the nude male centrefold and sexual hits, tips, tricks and more for women. Media Man friend, actor Jack Thompson, is tipped to have his racy centrefold recreated. Something about a 6th finger, down there.
ABC TV by all accounts have taken a calculated risk on the series. Most quarters of society, both insiders and outsiders we've chatted with believe the gamble will pay off with a tidy jackpot, and whispers already circulate as to how many awards the show and actors will pick up.
Nine's David Gyngell Respects Packer History; PBL Becomes Nine Entertainment Co...
KP put Publishing & Broadcasting Media on the map and grew it to become arguably the biggest media brands in Australia.
PBL - the name, is now history, since Bondi Beach based chief executive, David Gyngell, rebranded it with Nine Entertainment Co.
Gyngell, who announced the rebranding at Nine's 2011 program launch in Sydney on Friday, advised the new name would be more recognisable to the public and large and went on to emphasise Nine's broad range of businesses, which sport Nine, ACP Magazines, Ticketek and NineMSN.
The recognition factor is important since the firm is likely to be floated on the Australian Stock Exchange by its private equity owners, CVC Asia Pacific, in the first half of next year.
It's understood that a strong level of support from a host of retail investors will be key to the $5 billion-plus float's chances of a jackpot.
Gyngell wisely acknowledged it was not an easy decision given he is the late Kerry Packer's godson and great mate of James Packer. History buffs, just in case you wondered, PBL was formed way back in 1994 when KP merged Nine with ACP (Australian Consolidated Press).
"PBL has a long association with the Packers so personally I don't take that lightly. But it's modernising a business that needs to be publicly known. We don't have the luxury of having James Packer or another mogul giving the company real gravitas."
Other media updates down under include Network Seven being backed by Kerry Stokes and Network Ten's board now has James Packer, News Corporation director Lachlan Murdoch, mining magnate Gina Rinehart and WIN TV owner Bruce Gordon.
"Nine is the biggest thing that we have and it is also the thing that supports all the other companies in the best possible way," Gyngell said. "It will be a new year. We are starting again.
Nine confirmed its crime drama Underbelly would come back with a series set in the roaring 20s in Sydney as well as 3 Underbelly movies! And, get this, a good spot of gambling will also be featured.
Greg Tingle is a Special Contributor to the Gambling911.com website and Runs Media Man International.
In a strong rebuke to the Federal Circuit, a unanimous U.S. Supreme Court held?(pdf), on March 20, 2012, that Prometheus Laboratories? claims to methods of administering drugs to treat gastrointestinal autoimmune diseases do not meet the patentable subject matter standard of section 101 of the Patent Act.? The representative claim quoted by the Court recites, ?A method of optimizing therapeutic efficacy for treatment of an immune-mediated gastrointestinal disorder? comprising two steps: (a) administering one of a class of drugs (thiopurines) and (b) determining the level of a specified metabolite, ?wherein? a level below a given threshold ?indicates a need to increase the amount of said drug subsequently administered? [to improve efficacy], and a level above the threshold ?indicates a need to decrease the amount of said drug subsequently administered? [to avoid toxicity].
History of the Case. Mayo originally bought and used Prometheus test kits that employed the patented method, but it then decided to sell and market its own test, which was similar, but not identical.? Prometheus sued for patent infringement.? The district court found that Mayo?s test would infringe the Prometheus patents, but it then held the patents invalid as essentially claiming unpatentable laws of nature:? in this case, the relationship between the levels of the specified metabolite and the efficacy or toxicity of the relevant drugs.
The Federal Circuit reversed this decision in 2009, finding that the claims satisfied its then-controlling machine-or-transformation test.? Both the administering and determining stages, the court held, brought about a transformation of the patient?s body.? In the summer of 2010, while a Prometheus cert.petition (a request for Supreme Court review) was pending, the Supreme Court decided Bilski v. Kappos, a case involving a patent on a method of commodities hedging.? In a set of murky opinions, the Court held that the machine-or-transformation test was not the exclusive test of subject matter eligibility for method claims, but it could be helpful in appropriate cases.? Immediately thereafter, the Court ordered the Federal Circuit to reconsider its Prometheus opinion in light of Bilski.? In an opinion that might be described as perfunctory, the Federal Circuit held once more that the Prometheus patents comprised statutory subject matter, and the Supreme Court granted cert.
The Supreme Court?s Reasoning.?The Court?s opinion?(pdf) focuses on the difference between claims to laws of nature themselves and claims to specific applications of such laws: the former fail the section 101 subject matter test, while the latter pass.? The laws of nature involved here are the ?relationships between concentrations of certain metabolites in the blood and the likelihood that a dosage of a?? thiopurine drug will prove ineffective or cause harm.?? The legal question then becomes, ?do the patent claims add enough to their statements of the correlations to allow the processes they describe to qualify as patent-eligible processes that apply natural laws???For all nine members of the Court, the answer was a clear no.
The?Court?s analysis of the claims went through four steps.? First, it observed, the administering step just defines ?the relevant audience??doctors who treat patients with thiouprine drugs.? Second, ?the ?wherein? clauses simply tell a doctor about the relevant natural laws.?? Third, the determining step does not specify any particular process, but merely invites doctors ?to engage in well understood, routine, conventional activity.?? And fourth, ?to consider the three steps as an ordered combination adds nothing to the laws of nature that is not already present when the steps are considered separately.?? In sum, ?the three steps simply tell doctors to gather data from which they may draw an inference in light of the correlation.?? They ?are not sufficient to transform unpatentable natural correlations into patentable applications of those regularities.?? To allow such a patent could ?inhibit further discovery by improperly tying up the future use of laws of nature.?
What Do We Learn??The first point is that section 101 is alive and well as the first test of patentability.? Some recent Federal Circuit opinions have suggested that section 101 can and should be avoided in most cases, leaving the work of evaluating patents to sections 102 (novelty), 103 (nonobviousness), and 112 (written description).? The Court explicitly rejects that approach, refusing to let section 101, with its law of nature prohibition, become ?a dead letter.?? So the Patent Office and the courts will continue to have to make an initial determination of whether an invention comprises statutory subject matter, independent of whether it satisfies the other criteria of patentability.? Nonetheless, the language quoted above about ?well understood, routine, conventional activity? suggests that novelty and obviousness have some relevance to subject matter eligibility, despite loud protests that this conflates section 101 with issues presumably assigned to 102 and 103.
Second, although this opinion is light years ahead of Bilski in terms of clarity, it is still hard to be absolutely certain of what the subject matter test for method patents is.? We know?from the last paragraph of the opinion?that patents that ?effectively claim the underlying laws of nature themselves? are invalid.? Another version of this is that a survivable claim must ?differ significantly from a claim that just said ?apply the algorithm.?? But just how to identify such a claim is a more difficult issue.? We know that a claim structured just like Prometheus?s is invalid: that is, a claim that involves nothing more than gathering data that may provoke an inference based on a law of nature (for example, maybe, the claims upheld by the Federal Circuit on August 31, 2011 in Classen Immunotherapies, Inc. v. Biogen IDEC?).? Some additional application of the law of nature is required?but how much?
The Court rejects ?simply appending conventional steps, specified at high level of generality, to laws of nature.?? It expresses particular concern about claims so broad as to ?seek pre-empt the use? of the law of nature.? But it gives little affirmative guidance about how specific the application of the law must be, declining to speculate on precisely what additional limitations might have saved the Prometheus claims before it.
Impact on Myriad??There have already been a lot of questions raised about the impact of Prometheus on the Myriad litigation, in which a cert petition is still pending in the Supreme Court.? Does this new decision make it more or less likely that the Court will take Myriad? Does it suggest a likely outcome if the Court does take it?
Before speculating about these questions, it is important to remember that the Federal Circuit decision in Myriad addressed three separate sets of patent claims: (1) the court upheld (with a partial dissent) Myriad?s product claims on cDNA and isolated DNA; (2) the court also upheld Myriad?s claims to methods of screening potential cancer therapeutics by analyzing growth rates of cells with altered BRCA genes in the presence or absence of the treatments; but (3) the court rejected Myriad?s claims to methods of analyzing BRCA gene sequences and comparing those with cancer-predisposing mutations to normal sequences. The cert petitions filed by both sides do not address the methods claims (only the product claims and the highly technical standing issue), but the Supreme Court could order briefing and argument on any aspect of the case.
The Prometheus decision says nothing about gene product claims, so is irrelevant to issue (1) in Myriad. But it says a lot, obviously, about method claims that bear at least some structural similarity to those in Prometheus.? So does Prometheus indicate that the Court is more or less likely to review those method claims? (Warning: anyone who claims to have inside information about pending Supreme Court decisions is lying?Court security makes the old KGB look like a sieve.) Our guess (and it?s little more than that) is that the issuance of Prometheus makes it less likely that the Court would review the Myriad method claims.? It has just issued a unanimous and?by the standards of Supreme Court patent cases?relatively clear opinion on generally similar medical methods.? History suggests that is unlikely to want to revisit that topic the very next year.? Prometheus itself is an obvious exception, of course, coming right after Bilski. But the Court may have realized how unhelpful its fractured Bilski opinion was, and all of the justices apparently believed that the Federal Circuit had either failed to understand it or chosen to ignore it.? And the history of Prometheus suggests a possible pathway for Myriad: that the Supreme Court would grant cert, but (with respect to the method claims) for the limited purpose of vacating the Federal Circuit?s opinion and ordering reconsideration in light of Prometheus.
But if the Court does decide to review Myriad (or if the Federal Circuit is ordered to do it over), does Prometheus help us to predict the outcome?? The method claims that the Federal Circuit rejected ((3) above) are hard to distinguish from those in Prometheus: doctors gather information and make a straightforward comparison, using basic genetic knowledge.? Those claims are likely to be rejected once again.? The drug-screening claims that were upheld ((2) above) are a closer call.? If the ?algorithm? is the protocol for comparing the effects of treating or not treating cell lines, then ?do the patent claims add enough to their statements of the correlations [or algorithm] to allow the processes they describe to qualify as patent-eligible processes that apply natural laws??? There is a good bit of practical application going on here: cell lines must be grown and drugs applied (or not) before a judgment is made.? It looks more like a real-world pharmaceutical process than a broad statement of an algorithm.? For that reason, it seems more likely than not that this category of method claims would be upheld once again under section 101.
Conclusion. We now know considerably more about the Supreme Court?s views on methods than we did after the worse-than-useless Bilski opinion.? It is refreshing to these observers that the Court dove right back into method patents in an apparent effort to rectify the damage it did in Bilski (and there?s also some entertainment value in the revival of the Supreme Court-Federal Circuit tension that seemed to have abated a bit). But it also seems unlikely that the Court would go back to the method issue immediately, so we doubt that it will take that part of Myriad, except for the limited purpose of remanding to the Federal Circuit for reconsideration.
In terms of impact on the marketplace, there is, of course, serious impact if your business model depends on patents just like these (e.g., if you are Dr. Classen).? But for others, both in biotechnology and IT, the effect should be minimal.? Admittedly, the mere changing of the test from one that was formerly more inclusive to one that narrows eligibility is potentially destabilizing?under the former machine-or-transformation test, ?administering? and ?determining? steps were generally transformative and therefore corresponded with patent eligibility.? But the key word is potentially, since the Prometheus patents already reflected an extreme stretching of section 101?s limits, and were also?as the Federal Circuit pointed out in its 2009 opinion?highly suspect under sections 102 and 103.
Tags: ACLU/Myriad Litigation, Bilski, Bilski v. Kappos, Classen, Classen Immunotherapies v. Biogen IDEC, diagnostic method patents, diagnostic patents, law of nature, method patents, Myriad, Myriad Genetics, Prometheus Laboratories, Prometheus v. Mayo, Supreme Court
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Public release date: 28-Mar-2012
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In a strong rebuke to the Federal Circuit, a unanimous U.S. Supreme Court held?(pdf), on March 20, 2012, that Prometheus Laboratories? claims to methods of administering drugs to treat gastrointestinal autoimmune diseases do not meet the patentable subject matter standard of section 101 of the Patent Act.? The representative claim quoted by the Court recites, ?A method of optimizing therapeutic efficacy for treatment of an immune-mediated gastrointestinal disorder? comprising two steps: (a) administering one of a class of drugs (thiopurines) and (b) determining the level of a specified metabolite, ?wherein? a level below a given threshold ?indicates a need to increase the amount of said drug subsequently administered? [to improve efficacy], and a level above the threshold ?indicates a need to decrease the amount of said drug subsequently administered? [to avoid toxicity].